Juul Labs is working to expand the body of scientific knowledge around electronic nicotine delivery system (ENDS) products, which we believe can offer adult smokers a noncombustible alternative to combustible cigarettes and, in so doing, reduce the harm associated with tobacco use.

Nicotine is addictive and can be harmful, but it is not the primary cause of the harms associated with smoking combustible cigarettes. It is the toxicants in the smoke produced when tobacco leaves are burned (i.e., combusted) that are responsible for the vast majority of smoking-related death and disease.

With more innovative smokefree alternatives to cigarettes than ever before, there is an historic opportunity to make the combustible cigarette obsolete and end the unnecessary premature death and pervasive chronic illnesses caused by cigarette use. 

Juul Labs is committed to responsibly developing alternative nicotine products, backed by science and evidence. We support FDA’s regulatory oversight to authorize scientifically-validated smokefree products and have established a robust research program to support our regulatory filings.

As part of the Premarket Tobacco Product Application (PMTA) process, Juul Labs has built a comprehensive research program focused on examining the public health impact of the JUUL System. This includes research on our products’ impact on the individual user, ability to convert adult smokers from combustible cigarettes, and the net-population impact on public health. We’re exploring and supporting science and research in four key areas:

• Nonclinical Studies

  Our nonclinical research examines JUUL e-liquid and aerosol through various chemical and toxicological assessments in laboratory settings. This includes measuring and evaluating the levels of harmful and potentially harmful constituents (HPHCs) found in aerosol from the JUUL System compared to smoke from combustible cigarettes.

• Clinical Studies

  Our clinical studies examine the rate and level of nicotine absorption in the body, potential secondhand aerosol exposure in real world settings, and reductions in exposure to carcinogens and other harmful chemicals found in the smoke from combustible cigarettes.

• Behavioral Studies

  Through behavioral studies of tens of thousands of adult JUUL System users, we examine the real-life behavioral practices of adult smokers, including complete switching away from cigarettes.

• Economics and Policy Impact Studies

  Through our economics and policy impact research, we build causal inference, econometric, and statistical models that demonstrate the impact of ENDS product use, including the JUUL System, on a wide range of key population-level outcomes.

We are continuously examining the role electronic nicotine delivery systems (ENDS) products can play in a comprehensive public health strategy that incorporates tobacco harm reduction.